NREP Antikörper (AA 25-68)

Produktnummer ABIN668496

Produktdetails anti-NREP Antikörper

Target: NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))

Bindungsspezifität: AA 25-68

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NREP Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human P311

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-NREP Antikörper (ABIN668496)

Li, Yao, He, Gao, Bai, Yang, Zhang, Zhan, Tan, Zhou, Takata, Wu, Luo: "P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression." in: Stem cell research & therapy, Vol. 7, Issue 1, pp. 175, (2016) (PubMed).

Yao, Li, He, Yang, Zhang, Zhan, Xu, Tan, Zhou, Wu, Luo: "P311 Accelerates Skin Wound Reepithelialization by Promoting Epidermal Stem Cell Migration Through RhoA and Rac1 Activation." in: Stem cells and development, Vol. 26, Issue 6, pp. 451-460, (2016) (PubMed).

Yao, Yang, He, Li, Xu, Zhang, Li, Zhan, Sun, Tan, Zhou, Luo, Wu: "P311 promotes renal fibrosis via TGFβ1/Smad signaling." in: Scientific reports, Vol. 5, pp. 17032, (2015) (PubMed).

Yan, Zhang, Wang, Xu, Ren, Zhang, Shi, Chen, Shi, Tian, Zhao, Dong: "Significant reduction of the GLUT3 level, but not GLUT1 level, was observed in the brain tissues of several scrapie experimental animals and scrapie-infected cell lines." in: Molecular neurobiology, Vol. 49, Issue 2, pp. 991-1004, (2014) (PubMed).

Peng, Yuan, Tan, Ma, Bian, Xu, He, Cao, Huang, Cui, Gan, Wang, Zhou, Hu, Yang, Luo, Wu: "Identification of ITGB4BP as a new interaction protein of P311." in: Life sciences, Vol. 90, Issue 15-16, pp. 585-90, (2012) (PubMed).

Details zu NREP

Target: NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))

Andere Bezeichnung: P311 protein (C5orf13 Produkte)

Hintergrund:

Synonyms: P311, PTZ17, SEZ17, D4S114, C5orf13, PRO1873, Neuronal regeneration-related protein, Neuronal protein 3.1, Protein p311, NREP

Background: May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis (By similarity). Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3 (By similarity). May play a role in the regulation of alveolar generation.

Gen-ID: 9315

UniProt: Q16612