Thyroperoxidase Antikörper (AA 351-450)
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- Target Alle Thyroperoxidase (TPO) Antikörper anzeigen
- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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Bindungsspezifität
- AA 351-450
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Thyroperoxidase Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Ratte
- Homologie
- Mouse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from mouse Thyroid peroxidase
- Isotyp
- IgG
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- Applikationshinweise
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WB 1:300-5000
IF(IHC-P) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
- Andere Bezeichnung
- Thyroid peroxidase (TPO Produkte)
- Synonyme
- MSA antikoerper, TDH2A antikoerper, TPX antikoerper, TPO antikoerper, msa antikoerper, tpx antikoerper, xtpo antikoerper, LOC100218312 antikoerper, thyroid peroxidase antikoerper, TPO antikoerper, Tpo antikoerper, tpo antikoerper, LOC100547103 antikoerper
- Hintergrund
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Synonyms: Thyroid peroxidase, TPO
Background: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].
- Gen-ID
- 22018
- UniProt
- P35419
- Pathways
- Thyroid Hormone Synthesis
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