SLC5A5 Antikörper (AA 525-618)
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- Target Alle SLC5A5 Antikörper anzeigen
- SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))
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Bindungsspezifität
- AA 525-618
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Reaktivität
- Human, Ratte, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SLC5A5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Schwein, Ratte
- Homologie
- Mouse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from mouse NIS
- Isotyp
- IgG
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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Molecular Mechanisms of 2, 3', 4, 4', 5-Pentachlorobiphenyl-Induced Thyroid Dysfunction in FRTL-5 Cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120133, (2015) (PubMed).
: "Molecular mechanisms of human thyrocyte dysfunction induced by low concentrations of polychlorinated biphenyl 118 through the Akt/FoxO3a/NIS pathway." in: Journal of applied toxicology : JAT, Vol. 35, Issue 9, pp. 992-8, (2015) (PubMed).
: "Effect of sodium/iodide symporter (NIS)-mediated radioiodine therapy on estrogen receptor-negative breast cancer." in: Oncology reports, Vol. 34, Issue 1, pp. 59-66, (2015) (PubMed).
: "
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Molecular Mechanisms of 2, 3', 4, 4', 5-Pentachlorobiphenyl-Induced Thyroid Dysfunction in FRTL-5 Cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120133, (2015) (PubMed).
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- Target
- SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))
- Andere Bezeichnung
- NIS (SLC5A5 Produkte)
- Synonyme
- Na(+)/I(-) cotransporter antikoerper, Na(+)/I(-) symporter antikoerper, Nis antikoerper, solute carrier family 5 member 5 antikoerper, Slc5a5 antikoerper
- Hintergrund
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Synonyms: Na+/I- cotransporter, Na+/I- symporter, Na+/I- cotransporter, Na+/I- symporter, Na+/I- cotransporter, Na+/I-symporter, NIS, SC5A5_HUMAN, SLC5A5, sodium iodide symporter, Sodium-iodide symporter, Sodium/iodide cotransporter, Solute carrier family 5 sodium iodide symporter member 5, Solute carrier family 5, Solute carrier family 5 member 5.
Background: catalyzes Na+/I- symporter activity plays a role in iodide transport and thyroid hormone generation.Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.
- Gen-ID
- 114479
- UniProt
- Q99PN0
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