Interferon gamma Antikörper (AA 81-166)

Produktnummer ABIN669141

Produktdetails anti-Interferon gamma Antikörper

Target: Interferon gamma (IFNG)

Bindungsspezifität: AA 81-166

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Interferon gamma Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFN Gamma

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Interferon gamma Antikörper (ABIN669141)

Wang, Wang, Song, Chu, Qu: "Deficiency of interferon-gamma or its receptor promotes colorectal cancer development." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 35, Issue 4, pp. 273-80, (2015) (PubMed).

Nimmagadda, Bever, Vattikunta, Talat, Ahmad, Nagalla, Trisler, Judge, Royal, Chandrasekaran, Russell, Makar: "Overexpression of SIRT1 protein in neurons protects against experimental autoimmune encephalomyelitis through activation of multiple SIRT1 targets." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 9, pp. 4595-607, (2013) (PubMed).

Guo, Qian, Zhang: "Histopathology and immunohistochemical profile in idiopathic dacryoadenitis." in: Current eye research, Vol. 37, Issue 5, pp. 365-71, (2012) (PubMed).

Details zu Interferon gamma

Target: Interferon gamma (IFNG)

Andere Bezeichnung: IFN gamma (IFNG Produkte)

Synonyme: IFG antikoerper, IFI antikoerper, IFN-g antikoerper, Ifg antikoerper, IFNG2 antikoerper, IFN-gamma antikoerper, IFN-G antikoerper, IFNG antikoerper, IFNgamma antikoerper, TCRalpha antikoerper, INF-G antikoerper, ifng antikoerper, interferon gamma antikoerper, interferon, gamma 1-2 antikoerper, IFNG antikoerper, Ifng antikoerper, ifng1-2 antikoerper

Hintergrund:

Synonyms: IFG, IFI, Interferon gamma, IFN-gamma, Immune interferon, IFNG

Background: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.

Gen-ID: 3458

UniProt: P01579

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie