CCR2 Antikörper

Produktnummer ABIN670146

Produktdetails anti-CCR2 Antikörper

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CCR-2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P (1:100-500),IF (p) (1:100-500)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Referenzen für anti-CCR2 Antikörper (ABIN670146)

Li, Pang, Yu, Wu, Guo, Zhang: "Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke." in: Brain : a journal of neurology, Vol. 136, Issue Pt 12, pp. 3578-88, (2013) (PubMed).

Details zu CCR2

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Andere Bezeichnung: CCR-2 (CCR2 Produkte)

Synonyme: CC-CKR-2 antikoerper, CCR-2 antikoerper, CCR2A antikoerper, CCR2B antikoerper, CD192 antikoerper, CKR2 antikoerper, CKR2A antikoerper, CKR2B antikoerper, CMKBR2 antikoerper, MCP-1-R antikoerper, ACKR5 antikoerper, CKRX antikoerper, CRAM antikoerper, CRAM-A antikoerper, CRAM-B antikoerper, HCR antikoerper, Cc-ckr-2 antikoerper, Ccr2a antikoerper, Ccr2b antikoerper, Ckr2 antikoerper, Ckr2a antikoerper, Ckr2b antikoerper, Cmkbr2 antikoerper, mJe-r antikoerper, C-C motif chemokine receptor 2 antikoerper, C-C motif chemokine receptor like 2 antikoerper, chemokine (C-C motif) receptor 2 antikoerper, CCR2 antikoerper, CCRL2 antikoerper, Ccr2 antikoerper, LOC484790 antikoerper

Hintergrund:

Synonyms: C-C Chemokine receptor 2B, C C chemokine receptor type 2, C C CKR 2, CC chemokine receptor type 2, CC CKR 2, CCCKR2, CCR 2, CCR1L, CCR2A, CCR2B, CCR5L, CD192, CD192 antigen, Chemokine C C mot receptor 2, Chemokine CC Mot Receptor 2, CKR 2, CKR2, CKR2A, CKR2B, CMKBR2, MCP 1 R, MCP1 RECEPTOR, MCP1R, Monocyte chemoattractant protein 1 receptor, Monocyte Chemotactic Protein 1 Receptor, CCR2_HUMAN, C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CCR-2, CCR2, Monocyte chemoattractant protein 1 receptor, MCP-1-R.

Background: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].

Molekulargewicht: 41kDa

Gen-ID: 1231

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process