Adiponectin Receptor 1 Antikörper (AA 241-270)

Produktnummer ABIN670836

Produktdetails anti-Adiponectin Receptor 1 Antikörper

Target: Adiponectin Receptor 1 (ADIPOR1)

Bindungsspezifität: AA 241-270

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adiponectin Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Adiponectin Receptor 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Adiponectin Receptor 1 Antikörper (ABIN670836)

Wang, Gao, Lau, Wang, Liu, Li, Wang, Yuan, Koch, Ma: "G-protein-coupled receptor kinase 2-mediated desensitization of adiponectin receptor 1 in failing heart." in: Circulation, Vol. 131, Issue 16, pp. 1392-404, (2015) (PubMed).

Wu, Chio, Tsai, Chang, Lin, Huang, Lin: "Obesity Exacerbates Rat Cerebral Ischemic Injury through Enhancing Ischemic Adiponectin-Containing Neuronal Apoptosis." in: Molecular neurobiology, (2015) (PubMed).

Cao, Li, Luo, Li, Liu, Gao, Yin, Luan: "Molecular cloning and expression analysis of adiponectin and its receptors (AdipoR1 and AdipoR2) in the hypothalamus of the Huoyan goose during different stages of the egg-laying cycle." in: Reproductive biology and endocrinology : RB&E, Vol. 13, pp. 87, (2015) (PubMed).

Liu, Liang, Lau, Wang, Zhao, Li, Wang, Yuan, Lopez, Christopher, Xiao, Ma, Wang: "High glucose/High Lipids impair vascular adiponectin function via inhibition of caveolin-1/AdipoR1 signalsome formation." in: Free radical biology & medicine, Vol. 89, pp. 473-485, (2015) (PubMed).

Guo, Qi, Yu, Du, Wu, Liu: "Effect of exenatide on the cardiac expression of adiponectin receptor 1 and NADPH oxidase subunits and heart function in streptozotocin-induced diabetic rats." in: Diabetology & metabolic syndrome, Vol. 6, Issue 1, pp. 29, (2014) (PubMed).

Morad, Abrahamsson, Dabrosin: "Estradiol affects extracellular leptin:adiponectin ratio in human breast tissue in vivo." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 9, pp. 3460-7, (2014) (PubMed).

Ji, Wu, Ma, Ma, Qin: "The effect of resveratrol on the expression of AdipoR1 in kidneys of diabetic nephropathy." in: Molecular biology reports, Vol. 41, Issue 4, pp. 2151-9, (2014) (PubMed).

Li, Su, Zong: "Analysis of the association between adiponectin, adiponectin receptor 1 and diabetic cardiomyopathy." in: Experimental and therapeutic medicine, Vol. 7, Issue 4, pp. 1023-1027, (2014) (PubMed).

Guo, Qin, Zhang, Li, Yin: "Effect of rosiglitazone on the expression of cardiac adiponectin receptors and NADPH oxidase in type 2 diabetic rats." in: European journal of pharmacology, Vol. 685, Issue 1-3, pp. 116-25, (2012) (PubMed).

Guo, Zhang, Li, Xu: "Effect of telmisartan on the expression of adiponectin receptors and nicotinamide adenine dinucleotide phosphate oxidase in the heart and aorta in type 2 diabetic rats." in: Cardiovascular diabetology, Vol. 11, pp. 94, (2012) (PubMed).

Liu, Wu, Zhang, Chen, Liu, Wu, Zhu: "The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepatitis is associated with regulating adiponectin receptor expression in rats." in: European journal of pharmacology, Vol. 650, Issue 1, pp. 384-9, (2010) (PubMed).

Details zu Adiponectin Receptor 1

Target: Adiponectin Receptor 1 (ADIPOR1)

Andere Bezeichnung: Adiponectin Receptor 1 (ADIPOR1 Produkte)

Synonyme: ADIPOR1 antikoerper, adipor1 antikoerper, zgc:92893 antikoerper, ACDCR1 antikoerper, CGI45 antikoerper, PAQR1 antikoerper, TESBP1A antikoerper, 2810031L11Rik antikoerper, CGI-45 antikoerper, Paqr1 antikoerper, zgc:55386 antikoerper, wu:fj02d08 antikoerper, acdcr1 antikoerper, cgi-45 antikoerper, cgi45 antikoerper, paqr1 antikoerper, tesbp1a antikoerper, MGC53458 antikoerper, Adipor1 antikoerper, adiponectin receptor 1 antikoerper, adiponectin receptor 1a antikoerper, adiponectin receptor 1b antikoerper, adiponectin receptor 1 S homeolog antikoerper, adiponectin receptor 1 L homeolog antikoerper, ADIPOR1 antikoerper, adipor1a antikoerper, Adipor1 antikoerper, adipor1b antikoerper, adipor1 antikoerper, adipor1.S antikoerper, adipor1.L antikoerper

Hintergrund:

Synonyms: CGI45, PAQR1, ACDCR1, CGI-45, TESBP1A, Adiponectin receptor protein 1, Progestin and adipoQ receptor family member I, ADIPOR1

Background: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.

Gen-ID: 51094

UniProt: Q96A54

Pathways: AMPK Signaling