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Cyclin D3 Antikörper (AA 121-220)

Name: Cyclin D3 Antikörper (AA 121-220)
SKU: ABIN671571
Price: 384.62 EUR
Availability: InStock

CCND3 Reaktivität: Human, Kaninchen WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Formalin-fixed and paraffin embedded human breast carcinoma labeled Anti-Cyclin D3 Polyclonal Antibody, Unconjugated (ABIN671571) at 1:200, followed by conjugation to the secondary antibody and DAB staining (Cyclin D3 Antikörper (AA 121-220))

IHC

Formalin-fixed and paraffin embedded rabbit carotid artery labeled Anti-Cyclin D3 Polyclonal Antibody, Unconjugated (ABIN671571) at 1:200, followed by conjugation to the secondary antibody and DAB staining (Cyclin D3 Antikörper (AA 121-220))

IHC

Formalin-fixed and paraffin embedded rabbit carotid artery labeled Anti-Cyclin D3 Polyclonal Antibody, Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (Cyclin D3 Antikörper (AA 121-220))

IHC (p)

Formalin-fixed and paraffin embedded human breast carcinoma labeled Anti-Cyclin D3 Polyclonal Antibody, Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (Cyclin D3 Antikörper (AA 121-220))

IHC (p)

4 Abbildungen

(1 reference)

Produktnummer ABIN671571

Datenblatt (PDF)

Target Alle Cyclin D3 (CCND3) Antikörper anzeigen

Cyclin D3 (CCND3)
Bindungsspezifität
31

15

7

7

6

5

2

2

2

2

2

2

1

1

1

1

1

1

1
AA 121-220
Reaktivität
106

45

36

15

6

5

4

3

2

1

1

1

1
Human, Kaninchen
Wirt
92

16
Kaninchen
Passende Sekundärantikörper
Klonalität
85

23
Polyklonal
Konjugat
48

6

5

5

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Dieser Cyclin D3 Antikörper ist unkonjugiert
Applikation
78

33

30

26

25

18

15

14

9

7

6

4

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human, Kaninchen

Homologie

Mouse,Rat,Dog,Cow,Pig

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human Cyclin D3

Isotyp

IgG

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CCND3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin D3 (CCND3) (AA 136-292) antibody
CCND3 Reaktivität: Human, Ratte WB, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin D3 (CCND3) (AA 252-281), (C-Term) antibody
CCND3 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB43029 unconjugated

anti-Cyclin D3 (CCND3) (AA 1-292) antibody
CCND3 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin D3 (CCND3) (AA 1-292) antibody
CCND3 Reaktivität: Human WB, IHC (p), IF Wirt: Maus Polyclonal unconjugated

anti-Cyclin D3 (CCND3) (C-Term) antibody
CCND3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Schaf, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin D3 (CCND3) (AA 1-292) antibody
CCND3 Reaktivität: Human WB, ELISA, IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin D3 (CCND3) (AA 33-66), (N-Term) antibody
CCND3 Reaktivität: Ratte WB Wirt: Kaninchen Polyclonal RB43404 unconjugated

anti-Cyclin D3 (CCND3) (pThr283) antibody
CCND3 Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB42083 unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Souza, Silva, Calloway, Kucuk, Rossi, McLemore: "Genistein protects hematopoietic stem cells against G-CSF-induced DNA damage." in: Cancer prevention research (Philadelphia, Pa.), Vol. 7, Issue 5, pp. 534-44, (2014) (PubMed).
Target

Cyclin D3 (CCND3)

Andere Bezeichnung

Cyclin D3 (CCND3 Produkte)

Synonyme

zgc:103502 antikoerper, CCND3 antikoerper, 9230106B05Rik antikoerper, AA682053 antikoerper, AL024085 antikoerper, AW146355 antikoerper, C78795 antikoerper, cyclin D3 antikoerper, ccnd3 antikoerper, CCND3 antikoerper, Ccnd3 antikoerper

Hintergrund

Synonyms: G1/S-specific cyclin-D3, CCND3
Background: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

Gen-ID

896

UniProt

P30281

Pathways

Zellzyklus, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process