CD3 Antikörper (mFluor™450)

Produktnummer ABIN6731073

Produktdetails anti-CD3 Antikörper (mFluor™450)

Target: CD3

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3 Antikörper ist konjugiert mit mFluor™450

Applikation: Flow Cytometry (FACS)

Verwendungszweck: CD3 mFluor™ 450 Antibody

Produktmerkmale: The monoclonal UCHT1 clone recognizes CD3ε antigen, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain (zeta-chain) to generate an activation signal in T lymphocytes. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition. Crosslinking of the TCR via plate bound UCHT1 monoclonal is widely used to study the activation T cell response in vitro.

Aufreinigung: Purified

Reinheit: >95 %

Güteklasse: GMP Grade

Immunogen: Thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor

Klon: UCHT1

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C, Conjugated antibodies should never be frozen.

Details zu CD3

Target: CD3

Andere Bezeichnung: CD3 (CD3 Produkte)

Gen-ID: 916

NCBI Accession: NM_000733

UniProt: P07766

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway