TRAF1 Antikörper (AA 301-416) (Cy3)

Produktnummer ABIN673467

Produktdetails anti-TRAF1 Antikörper (Cy3)

Target: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Bindungsspezifität: AA 301-416

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF1 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TRAF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TRAF1

Target: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Andere Bezeichnung: TRAF1 (TRAF1 Produkte)

Synonyme: CG3048 antikoerper, DTRAF antikoerper, DTRAF1 antikoerper, Dmel\\CG3048 antikoerper, TRAF antikoerper, TRAF1 antikoerper, Traf1 antikoerper, dTRAF antikoerper, dTRAF1 antikoerper, dTraf1 antikoerper, dtraf1 antikoerper, traf1 antikoerper, traf4 antikoerper, DKFZp469G032 antikoerper, EBI6 antikoerper, MGC:10353 antikoerper, 4732496E14Rik antikoerper, TNF receptor associated factor 1 antikoerper, TNF-receptor-associated factor 4 antikoerper, TNF receptor-associated factor 1 antikoerper, TRAF1 antikoerper, Traf4 antikoerper, Traf1 antikoerper, traf1 antikoerper

Hintergrund:

Synonyms: EBI6, MGC:10353, TNF receptor-associated factor 1, Epstein-Barr virus-induced protein 6, TRAF1

Background: Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

Gen-ID: 7185

UniProt: Q13077

Pathways: NF-kappaB Signalweg, Apoptose, Cell-Cell Junction Organization, Asymmetric Protein Localization