BRD2 Antikörper (AA 524-573)

Produktnummer ABIN214728

Produktdetails anti-BRD2 Antikörper

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Bindungsspezifität: AA 524-573

Reaktivität: Human, Rind (Kuh), Maus, Hund, Pferd, Ratte, Schwein, Hamster, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human BRD2

Homologie: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Pig (100%) Xenopus (92%) Zebrafish (91%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa524-573 of human BRD2 (P25440, NP_005095). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Pig, Opossum (100%), Xenopus (92%), Zebrafish (91%), Guinea pig (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Details zu BRD2

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Andere Bezeichnung: BRD2 / RING3 (BRD2 Produkte)

Synonyme: D6S113E antikoerper, FSH antikoerper, FSRG1 antikoerper, NAT antikoerper, RING3 antikoerper, RNF3 antikoerper, AW228947 antikoerper, D17H6S113E antikoerper, Frg-1 antikoerper, Fsrg-1 antikoerper, Fsrg1 antikoerper, Nat antikoerper, Ring3 antikoerper, Rnf3 antikoerper, mKIAA4005 antikoerper, brd2-a antikoerper, fsh antikoerper, fsrg1 antikoerper, nat antikoerper, ring3 antikoerper, rnf3 antikoerper, brd2 antikoerper, fe47f02 antikoerper, fi85h05 antikoerper, wu:fe47f02 antikoerper, wu:fi85h05 antikoerper, Ring3 protein antikoerper, bromodomain containing 2 antikoerper, bromodomain containing 2 S homeolog antikoerper, bromodomain containing 2a antikoerper, CHLREDRAFT_190116 antikoerper, CHLREDRAFT_150233 antikoerper, CHLREDRAFT_182576 antikoerper, CHLREDRAFT_188250 antikoerper, BRD2 antikoerper, Brd2 antikoerper, brd2.S antikoerper, brd2a antikoerper

Hintergrund: Name/Gene ID: BRD2
Subfamily: BRD
Family: Protein Kinase

Synonyms: BRD2, Bromodomain containing 2, FSRG1, KIAA9001, NaT, RING3, RNF3, O27.1.1, Bromodomain-containing 2, D6S113E, FSH

Gen-ID: 6046

NCBI Accession: NP_005095

UniProt: P25440

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion