MUC1 Antikörper (AA 1051-1255)
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- Target Alle MUC1 Antikörper anzeigen
- MUC1 (Mucin 1 (MUC1))
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Bindungsspezifität
- AA 1051-1255
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MUC1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Dog,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MUC1
- Isotyp
- IgG
- Top Product
- Discover our top product MUC1 Primärantikörper
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- Applikationshinweise
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ELISA 1:500-1000
IHC-P 1:200-400 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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Chemiluminescence imaging immunoassay of multiple tumor markers for cancer screening." in: Analytical chemistry, Vol. 84, Issue 5, pp. 2410-5, (2012) (PubMed).
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Chemiluminescence imaging immunoassay of multiple tumor markers for cancer screening." in: Analytical chemistry, Vol. 84, Issue 5, pp. 2410-5, (2012) (PubMed).
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- Target
- MUC1 (Mucin 1 (MUC1))
- Andere Bezeichnung
- MUC1 (MUC1 Produkte)
- Synonyme
- CA 15-3 antikoerper, CD227 antikoerper, EMA antikoerper, H23AG antikoerper, KL-6 antikoerper, MAM6 antikoerper, MCKD1 antikoerper, MUC-1 antikoerper, MUC-1/SEC antikoerper, MUC-1/X antikoerper, MUC1/ZD antikoerper, PEM antikoerper, PEMT antikoerper, PUM antikoerper, Muc-1 antikoerper, mucin 1, cell surface associated antikoerper, mucin 1, transmembrane antikoerper, MUC1 antikoerper, Muc1 antikoerper
- Hintergrund
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Synonyms: EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC, Mucin-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, Carcinoma-associated mucin, Episialin, Krebs von den Lungen-6, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin, MUC1
Background: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
- Gen-ID
- 4582
- UniProt
- P15941
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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