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Reticulon 4 Antikörper (AA 251-357)

RTN4 Reaktivität: Human, Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN674859
  • Target Alle Reticulon 4 (RTN4) Antikörper anzeigen
    Reticulon 4 (RTN4)
    Bindungsspezifität
    • 16
    • 14
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-357
    Reaktivität
    • 74
    • 54
    • 44
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 71
    • 3
    • 3
    • 2
    • 2
    Kaninchen
    Klonalität
    • 68
    • 13
    Polyklonal
    Konjugat
    • 35
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser Reticulon 4 Antikörper ist unkonjugiert
    Applikation
    • 64
    • 27
    • 26
    • 20
    • 17
    • 17
    • 17
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    Based on the location of the target sequence this antibody will recognize all isoforms(Nogo-A, Nogo-B, and Nogo-C).
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Sheep
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from Mouse Reticulon 4
    Isotyp
    IgG
    Top Product
    Discover our top product RTN4 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Reticulon 4 (RTN4)
    Andere Bezeichnung
    Reticulon 4 (RTN4 Produkte)
    Synonyme
    ASY antikoerper, NI220/250 antikoerper, NOGO antikoerper, NOGO-A antikoerper, NOGOC antikoerper, NSP antikoerper, NSP-CL antikoerper, Nbla00271 antikoerper, Nbla10545 antikoerper, Nogo-B antikoerper, Nogo-C antikoerper, RTN-X antikoerper, RTN4-A antikoerper, RTN4-B1 antikoerper, RTN4-B2 antikoerper, RTN4-C antikoerper, RTN4-Cw antikoerper, DKFZp459C0314 antikoerper, 1110020G17Rik antikoerper, AA407876 antikoerper, AA409940 antikoerper, AA960376 antikoerper, C130026I10Rik antikoerper, NgA antikoerper, Nogo-A antikoerper, mKIAA0886 antikoerper, mKIAA4153 antikoerper, NI-250 antikoerper, Nogo antikoerper, Vp20 antikoerper, r antikoerper, rat N antikoerper, rat NogoA antikoerper, reticulon-4 antikoerper, nogo antikoerper, rtn4 antikoerper, wu:fb17a02 antikoerper, wu:fb22f12 antikoerper, wu:fd61a07 antikoerper, zgc:92163 antikoerper, reticulon 4 antikoerper, reticulon 4a antikoerper, RTN4 antikoerper, rtn4 antikoerper, Rtn4 antikoerper, rtn4a antikoerper
    Hintergrund

    Synonyms: Reticulon-4, Rtn4, Neurite outgrowth inhibitor, Nogo protein, Foocen, Neuroendocrine-specific protein, NSP, euroendocrine-specific protein C homolog, RTN-x, Reticulon-5, RTN 4A, Nogo-A, RTN-xL, RTN 4B, ASY, Nogo-B, RTN-xS, Foocen-M, RTN 4C, Nogo-C, Foocen-S, RTN4-B2, Rtn-T

    Background: Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The reticulon protein is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Reticulon 4 regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. It regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. May inhibit BACE1 activity and amyloid precursor protein processing.

    Gen-ID
    68585
    UniProt
    Q99P72
    Pathways
    Neurotrophin Signalübertragung, Regulation of Cell Size, SARS-CoV-2 Protein Interaktom
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