SCGB1A1 Antikörper (AA 51-96)

Produktnummer ABIN675563

Produktdetails anti-SCGB1A1 Antikörper

Target: SCGB1A1 (Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1))

Bindungsspezifität: AA 51-96

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCGB1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Uteroglobin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SCGB1A1

Target: SCGB1A1 (Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1))

Andere Bezeichnung: Uteroglobin (SCGB1A1 Produkte)

Synonyme: CC10 antikoerper, CC16 antikoerper, CCPBP antikoerper, CCSP antikoerper, UGB antikoerper, UP-1 antikoerper, UP1 antikoerper, UGL antikoerper, PCB-BP antikoerper, UG antikoerper, Utg antikoerper, PCBB antikoerper, Ugb antikoerper, SCGB1A1 antikoerper, secretoglobin family 1A member 1 antikoerper, secretoglobin, family 1A, member 1 (uteroglobin) antikoerper, urinary protein 2 antikoerper, SCGB1A1 antikoerper, Scgb1a1 antikoerper, Rup2 antikoerper

Hintergrund:

Synonyms: Scgb1a1, secretoglobin family 1A member 1, UG, UGB, Utg, CC10, CC16, CCSP, PCB-BP, Clara cell 17 kDa protein, Clara cell phospholipid-binding prote, CCPBP, Clara cells 10 kDa secretory protein, PCB-binding protein, Urinary Protein 1, Urine Protein 1.

Background: Uteroglobin belongs to the family of secretoglobins and is a secreted protein product of nonciliated bronchiolar Clara cells. There is convincing data suggesting it has phospholipase A2 inhibitory activity, as well as, a number of other immunomodulatory features including inhibition of interferon gamma signalling and Th1 vs. Th2 lymphocyte regulation. It was proposed as a potential peripheral marker of respiratory epithelial injury and bronchial dysfunction. Clara Cell Protein 16 concentrations have been determined in both serum and bronchoalveolar lavage fluid in numerous studies since 1994. In serum, its increase is associated with age, asbestos, nitrogen chloride and ozone exposure, sarcoidosis and high PEEP ventilation. Decreased serum CC16 levels are found after pulmonary resection, in silica-exposed workers, smokers and in asthma. Decreased CC16 concentrations were also found in the amniotic fluid of fetuses suffering from pulmonary hypoplasia caused by various mechanisms (diaphragmatic hernia, diabetic fetopathy, Turner and Down syndrome). In pleural effusions, the CC16 concentration appears to be associated with its diffusion from the lung as evidenced by high CC16 levels in cardiac pleural congestion.

Gen-ID: 22287

UniProt: Q06318