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ITGAV/ITGB1 Antikörper

ITGAV/ITGB1 Reaktivität: Human, Maus, Ratte WB, FACS, IF (cc), ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN676718
  • Target Alle ITGAV/ITGB1 Produkte
    ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
    Reaktivität
    • 18
    • 18
    • 18
    • 3
    • 3
    • 3
    Human, Maus, Ratte
    Wirt
    • 18
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ITGAV/ITGB1 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Hendesi, Barbe, Safadi, Monroy, Popoff: "Integrin mediated adhesion of osteoblasts to connective tissue growth factor (CTGF/CCN2) induces cytoskeleton reorganization and cell differentiation." in: PLoS ONE, Vol. 10, Issue 2, pp. e0115325, (2015) (PubMed).

  • Target
    ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
    Andere Bezeichnung
    Integrin Alpha V + Beta 1 (ITGAV/ITGB1 Produkte)
    Hintergrund

    Synonyms: Integrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51 Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29

    Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro).

    Gen-ID
    3685, 3688
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