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ITGAV/ITGB1 Antikörper (Cy5)

ITGAV/ITGB1 Reaktivität: Human, Maus, Ratte WB, FACS, IF (cc) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN676722
  • Target Alle ITGAV/ITGB1 Produkte
    ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
    Reaktivität
    • 18
    • 18
    • 18
    • 3
    • 3
    • 3
    Human, Maus, Ratte
    Wirt
    • 18
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ITGAV/ITGB1 Antikörper ist konjugiert mit Cy5
    Applikation
    • 18
    • 16
    • 12
    • 3
    • 3
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1
    Isotyp
    IgG
  • Applikationshinweise
    FCM 1:20-100
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
    Abstract
    ITGAV/ITGB1 Produkte
    Sub Type
    Cocktail
    Hintergrund

    Synonyms: Integrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51 Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29

    Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro).

    Gen-ID
    3685, 3688
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