Integrin alpha 1 Antikörper (AA 1001-1179)

Produktnummer ABIN677483

Produktdetails anti-Integrin alpha 1 Antikörper

Target: Integrin alpha 1 (ITGA1)

Bindungsspezifität: AA 1001-1179

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Integrin alpha 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody may also detect integrin alpha L due to a 75 % non-contiguous sequence similarity in the corresponding immunogen region.

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Integrin alpha 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Integrin alpha 1 Antikörper (ABIN677483)

Zhang, Wang, Zhang, Zhang, Guo, Luo, Zhou, He, Zhang: "Rho/MRTF-A-Induced Integrin Expression Regulates Angiogenesis in Differentiated Multipotent Mesenchymal Stem Cells." in: Stem cells international, Vol. 2015, pp. 534758, (2015) (PubMed).

Details zu Integrin alpha 1

Target: Integrin alpha 1 (ITGA1)

Andere Bezeichnung: Integrin alpha 1 (ITGA1 Produkte)

Synonyme: CD49A antikoerper, E130012M19Rik antikoerper, Vla1 antikoerper, CD49a antikoerper, VLA1 antikoerper, integrin alpha 1 antikoerper, integrin subunit alpha 1 antikoerper, Itga1 antikoerper, ITGA1 antikoerper

Hintergrund:

Synonyms: VLA1, CD49a, Integrin alpha-1, CD49 antigen-like family member A, Laminin and collagen receptor, VLA-1, ITGA1

Background: Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.

Gen-ID: 3672

UniProt: P56199

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex