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ARHGEF2 Antikörper (pSer886)

ARHGEF2 Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN678563
  • Target Alle ARHGEF2 Antikörper anzeigen
    ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))
    Bindungsspezifität
    • 14
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer886
    Reaktivität
    • 60
    • 30
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 54
    • 7
    • 2
    Kaninchen
    Klonalität
    • 50
    • 13
    Polyklonal
    Konjugat
    • 35
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARHGEF2 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 19
    • 14
    • 14
    • 10
    • 8
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Arhgef2 around the phosphorylation site of Ser886
    Isotyp
    IgG
    Top Product
    Discover our top product ARHGEF2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))
    Andere Bezeichnung
    GEF H1 (ARHGEF2 Produkte)
    Synonyme
    MGC82333 antikoerper, MGC86214 antikoerper, MGC75855 antikoerper, AA408978 antikoerper, GEF antikoerper, GEF-H1 antikoerper, GEFH1 antikoerper, LFP40 antikoerper, Lbcl1 antikoerper, Lfc antikoerper, P40 antikoerper, mKIAA0651 antikoerper, GEF-H1/LFC antikoerper, Rho/Rac guanine nucleotide exchange factor 2 antikoerper, Rho/Rac guanine nucleotide exchange factor 2 S homeolog antikoerper, rho/rac guanine nucleotide exchange factor (GEF) 2 antikoerper, ARHGEF2 antikoerper, arhgef2.S antikoerper, arhgef2 antikoerper, Arhgef2 antikoerper
    Hintergrund

    Synonyms: GEF H1phospho S886, Arhgef2Ser886, Lbcl1, Lfc, mKIAA0651, AA408978, ARHG2, ARHGEF 2, ARHGEF-2, ARHGEF2, GEF, GEF H1, GEF-H1, GEFH1, LFP40, MGC95068, P40, Prolerating cell nucleolar antigen p40, Protein GEF-H1, rho/rac guanine nucleotide exchange factor GEF 2, rho/rac guanine nucleotide exchange factor 2, rho/rac guanine nucleotide exchange factor.

    Background: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.

    Gen-ID
    9181
    Pathways
    Negative Regulation of intrinsic apoptotic Signaling
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