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tau Antikörper (pThr548) (HRP)

Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN680057
  • Target Alle tau Antikörper anzeigen
    tau (tau Protein)
    Bindungsspezifität
    • 31
    • 31
    • 30
    • 29
    • 27
    • 27
    • 25
    • 25
    • 24
    • 24
    • 24
    • 23
    • 23
    • 22
    • 17
    • 17
    • 17
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 12
    • 11
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    pThr548
    Reaktivität
    • 579
    • 541
    • 538
    • 42
    • 28
    • 27
    • 18
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 684
    • 38
    • 3
    • 2
    Kaninchen
    Klonalität
    • 661
    • 65
    • 1
    Polyklonal
    Konjugat
    • 239
    • 40
    • 30
    • 29
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 24
    • 22
    • 22
    • 15
    • 15
    • 15
    • 15
    • 15
    • 15
    • 12
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Dieser tau Antikörper ist konjugiert mit HRP
    Applikation
    • 570
    • 272
    • 263
    • 213
    • 92
    • 85
    • 68
    • 58
    • 54
    • 37
    • 34
    • 17
    • 12
    • 12
    • 12
    • 9
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Tau around the phosphorylation site of Thr548 [VR(p-T)PP]
    Isotyp
    IgG
    Top Product
    Discover our top product tau Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    tau (tau Protein)
    Andere Bezeichnung
    Tau (tau Produkte)
    Synonyme
    DDPAC antikoerper, FTDP-17 antikoerper, MAPTL antikoerper, MSTD antikoerper, MTBT1 antikoerper, MTBT2 antikoerper, PPND antikoerper, TAU antikoerper, tau antikoerper, PHF-tau antikoerper, microtubule associated protein tau antikoerper, MAPT antikoerper
    Hintergrund

    Synonyms: TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, PPP1R13, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT

    Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

    Gen-ID
    4137
    UniProt
    P10636
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