CYP3A4 Antikörper
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- Target Alle CYP3A4 Antikörper anzeigen
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Huhn
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYP3A4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Huhn, Rind (Kuh), Hund, Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CYP3A1
- Isotyp
- IgG
- Top Product
- Discover our top product CYP3A4 Primärantikörper
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- Applikationshinweise
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WB(1:100-500)
Optimal working dilution should be determined by the investigator. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
- Andere Bezeichnung
- CYP3A4 (CYP3A4 Produkte)
- Synonyme
- CP33 antikoerper, CP34 antikoerper, CYP3A antikoerper, CYP3A3 antikoerper, CYPIIIA3 antikoerper, CYPIIIA4 antikoerper, HLP antikoerper, NF-25 antikoerper, P450C3 antikoerper, P450PCN1 antikoerper, MGC108372 antikoerper, CYP3A80 antikoerper, CYP3A4 antikoerper, CYP3A21 antikoerper, CYPIIIA21 antikoerper, CYP3A12 antikoerper, cytochrome P450 family 3 subfamily A member 4 antikoerper, cytochrome P450 family 3 subfamily A member 43 antikoerper, cytochrome P450 3A4 antikoerper, cytochrome P450, subfamily IIIA, polypeptide 4 antikoerper, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antikoerper, cytochrome P450, family 3, subfamily A, polypeptide 4 antikoerper, CYP3A4 antikoerper, CYP3A43 antikoerper, PTRG_01782 antikoerper, PTRG_06060 antikoerper, cyp3a4 antikoerper
- Hintergrund
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Synonyms: CP33, CP34, CYP3A, CYP3A1, CYP3A3, CYP3A4, CYPIIIA4, Cytochrome P450 3A4, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 subfamily IIIA polypeptide 3, Cytochrome P450 subfamily IIIA polypeptide 4, cytochrome P450, family 3, subfamily a, polypeptide 1, glucocorticoid inducible P450, HLP, MGC126680, NF 25, NF25, Nedipine oxidase, Niphedipine oxidase, P450 III steroid inducible, P450 PCNPCNC inducible, P450 PCN1, P450C3, P450PCN1, Quinine 3 monooxygenase, Taurochenodeoxycholate 6 alpha hydroxylase, CP3A4_HUMAN.
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist, however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].
- Molekulargewicht
- 58kDa
- Gen-ID
- 1576
- Pathways
- Steroid Hormone Biosynthesis
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