NOTCH2 Antikörper (AA 1501-1700)
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- Target Alle NOTCH2 Antikörper anzeigen
- NOTCH2 (Notch 2 (NOTCH2))
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Bindungsspezifität
- AA 1501-1700
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NOTCH2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus
- Homologie
- Rat,Pig,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Notch2
- Isotyp
- IgG
- Top Product
- Discover our top product NOTCH2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- NOTCH2 (Notch 2 (NOTCH2))
- Andere Bezeichnung
- Notch 2 (NOTCH2 Produkte)
- Synonyme
- AGS2 antikoerper, HJCYS antikoerper, hN2 antikoerper, AI853703 antikoerper, N2 antikoerper, notch6 antikoerper, sb:cb884 antikoerper, neurogenic locus notch homolog protein 2 antikoerper, notch 2 antikoerper, notch 3 antikoerper, LOC581186 antikoerper, NOTCH2 antikoerper, notch3 antikoerper, Notch2 antikoerper, notch2 antikoerper
- Hintergrund
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Synonyms: hN2, AGS2, HJCYS, Neurogenic locus notch homolog protein 2, Notch 2, NOTCH2
Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation.
- Gen-ID
- 4853
- UniProt
- Q04721
- Pathways
- Notch Signalweg, Stem Cell Maintenance
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