LAMP2 Antikörper (AA 301-411)

Produktnummer ABIN680198

Produktdetails anti-LAMP2 Antikörper

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Bindungsspezifität: AA 301-411

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Maus, Schwein, Ratte

Homologie: Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LAMP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-LAMP2 Antikörper (ABIN680198)

Iwao, Ojima, Kobayashi, Kishi, Nara, Esaki, Shimada, Hiraoka, Tanabe, Kanai: "Liver atrophy after percutaneous transhepatic portal embolization occurs in two histological phases: Hepatocellular atrophy followed by apoptosis." in: World journal of hepatology, Vol. 9, Issue 32, pp. 1227-1238, (2017) (PubMed).

Luks, Sacchi, Pollegioni, Dietrich: "Novel insights into renal D-amino acid oxidase accumulation: propiverine changes DAAO localization and peroxisomal size in vivo." in: Archives of toxicology, Vol. 91, Issue 1, pp. 427-437, (2016) (PubMed).

Kameyama, Nakajima, Nishitsuji, Mikawa, Uchimura, Kobayashi, Okuhira, Saito, Sakashita: "Iowa Mutant Apolipoprotein A-I (ApoA-IIowa) Fibrils Target Lysosomes." in: Scientific reports, Vol. 6, pp. 30391, (2016) (PubMed).

Sun, Nie, Wang, Yang, Meng, Xiao, Xiang, Li, Fu, Wang: "Factors that Affect Pancreatic Islet Cell Autophagy in Adult Rats: Evaluation of a Calorie-Restricted Diet and a High-Fat Diet." in: PLoS ONE, Vol. 11, Issue 3, pp. e0151104, (2016) (PubMed).

Zhang, Fu, Sheng, Li, Song, Li, Song, Wang, Chen, Yu, Wei: "Bone marrow CD11b(+)F4/80(+) dendritic cells ameliorate collagen-induced arthritis through modulating the balance between Treg and Th17." in: International immunopharmacology, Vol. 25, Issue 1, pp. 96-105, (2015) (PubMed).

Details zu LAMP2

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Andere Bezeichnung: Lamp2 (LAMP2 Produkte)

Synonyme: CD107b antikoerper, LAMP-2 antikoerper, LAMPB antikoerper, LGP110 antikoerper, Lamp-2 antikoerper, Lamp-2a antikoerper, Lamp-2b antikoerper, Lamp-2c antikoerper, Mac3 antikoerper, cd107b antikoerper, lamp-2 antikoerper, lampb antikoerper, LAMP2 antikoerper, lamp2 antikoerper, DKFZp459J126 antikoerper, LGP-B antikoerper, sb:cb587 antikoerper, wu:fb14a06 antikoerper, zgc:103532 antikoerper, lysosomal associated membrane protein 2 antikoerper, lysosomal-associated membrane protein 2 antikoerper, lysosomal-associated membrane protein 2 S homeolog antikoerper, lysosomal membrane glycoprotein 2 antikoerper, LAMP2 antikoerper, Lamp2 antikoerper, lamp2.S antikoerper, lamp2 antikoerper

Hintergrund:

Synonyms: LAMPB, CD107b, LAMP-2, LGP110, Lysosome-associated membrane glycoprotein 2, Lysosome-associated membrane protein 2, CD107 antigen-like family member B, LAMP2

Background: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.

Gen-ID: 3920

UniProt: P13473

Pathways: Autophagie