Claudin 4 Antikörper (AA 21-120)

Produktnummer ABIN680743

Produktdetails anti-Claudin 4 Antikörper

Target: Claudin 4 (CLDN4)

Bindungsspezifität: AA 21-120

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLDN4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Claudin 4 Antikörper (ABIN680743)

Wang, Chen, Liang, Yan, Lin, Liu, Luo, Huang, Li, Liu, Tang: "Notch inhibition promotes fetal liver stem/progenitor cells differentiation into hepatocytes via the inhibition of HNF-1?." in: Cell and tissue research, Vol. 357, Issue 1, pp. 173-84, (2014) (PubMed).

Details zu Claudin 4

Target: Claudin 4 (CLDN4)

Andere Bezeichnung: Claudin 4 (CLDN4 Produkte)

Synonyme: CPE-R antikoerper, CPER antikoerper, CPETR antikoerper, CPETR1 antikoerper, WBSCR8 antikoerper, hCPE-R antikoerper, Cep-r antikoerper, Cpetr antikoerper, Cpetr1 antikoerper, CLDN4 antikoerper, cper antikoerper, cpe-r antikoerper, cpetr antikoerper, cpetr1 antikoerper, hcpe-r antikoerper, wbscr8 antikoerper, claudin 4 antikoerper, claudin 4 L homeolog antikoerper, CLDN4 antikoerper, Cldn4 antikoerper, cldn4 antikoerper, cldn4.L antikoerper

Hintergrund:

Synonyms: CPER, CPE-R, CPETR, CPETR1, WBSCR8, hCPE-R, Claudin-4, Clostridium perfringens enterotoxin receptor, CPE-receptor, Williams-Beuren syndrome chromosomal region 8 protein, CLDN4

Background: Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact made up of network of strands that act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.

Gen-ID: 1364

UniProt: O14493

Pathways: Hepatitis C