ASB2 Antikörper (AA 501-587) (Biotin)

Produktnummer ABIN681090

Produktdetails anti-ASB2 Antikörper (Biotin)

Target: ASB2 (Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))

Bindungsspezifität: AA 501-587

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASB2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ASB2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ASB2

Target: ASB2 (Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))

Andere Bezeichnung: ASB2 (ASB2 Produkte)

Synonyme: ASB-2 antikoerper, 1110008E15Rik antikoerper, ASB2 antikoerper, asb2 antikoerper, zgc:77223 antikoerper, ankyrin repeat and SOCS box containing 2 antikoerper, ankyrin repeat and SOCS box-containing 2 antikoerper, ankyrin repeat and SOCS box containing 2b antikoerper, ASB2 antikoerper, Asb2 antikoerper, asb2b antikoerper

Hintergrund:

Synonyms: Ankyrin repeat and SOCS box 2 containing protein, Ankyrin repeat and SOCS box containing 2, Ankyrin repeat and SOCS box containing protein 2, Ankyrin repeat containing protein ASB2.ASB2_HUMAN

Background: The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Gen-ID: 51676