LPAR1 Antikörper (AA 281-364)

Produktnummer ABIN681103

Produktdetails anti-LPAR1 Antikörper

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Bindungsspezifität: AA 281-364

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LPAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EDG2/LPAR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-LPAR1 Antikörper (ABIN681103)

Chen, Zhang, Deng, Liu, Yang, Wu, Yu: "Lysophosphatidic acid directly induces macrophage-derived foam cell formation by blocking the expression of SRBI." in: Biochemical and biophysical research communications, Vol. 491, Issue 3, pp. 587-594, (2017) (PubMed).

Details zu LPAR1

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Andere Bezeichnung: LPAR1 (LPAR1 Produkte)

Synonyme: EDG2 antikoerper, GPR26 antikoerper, Gpcr26 antikoerper, LPA1 antikoerper, Mrec1.3 antikoerper, VZG1 antikoerper, edg-2 antikoerper, rec.1.3 antikoerper, vzg-1 antikoerper, Edg2 antikoerper, EDG-2 antikoerper, 5031439C20 antikoerper, AI326300 antikoerper, Kdt2 antikoerper, lpA1 antikoerper, edg2 antikoerper, si:dz22b13.1 antikoerper, si:dz46m7.1 antikoerper, zgc:92157 antikoerper, LPA receptor 1-A antikoerper, LPA-1-A antikoerper, gpr26 antikoerper, lpa1 antikoerper, lpa1r antikoerper, lpa1r1 antikoerper, lpar1 antikoerper, lpar1-a antikoerper, lpar1-b antikoerper, vzg1 antikoerper, xLPA1-1 antikoerper, LPA receptor 1-B antikoerper, LPA-1-B antikoerper, edg2-A antikoerper, xLPA1-2 antikoerper, xlpa1R antikoerper, lysophosphatidic acid receptor 1 antikoerper, lysophosphatidic acid receptor 1 S homeolog antikoerper, lysophosphatidic acid receptor 1 L homeolog antikoerper, LPAR1 antikoerper, Lpar1 antikoerper, lpar1 antikoerper, lpar1.S antikoerper, lpar1.L antikoerper

Hintergrund:

Synonyms: EDG2, LPA1, VZG1, GPR26, edg-2, vzg-1, Gpcr26, Mrec1.3, rec.1.3, Lysophosphatidic acid receptor 1, LPA receptor 1, LPA-1, Lysophosphatidic acid receptor Edg-2, LPAR1

Background: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.

Gen-ID: 1902

UniProt: Q92633

Pathways: Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration