PARD3 Antikörper (AA 1201-1356)

Produktnummer ABIN681718

Produktdetails anti-PARD3 Antikörper

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Bindungsspezifität: AA 1201-1356

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PARD-3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PARD3

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Andere Bezeichnung: PARD-3 (PARD3 Produkte)

Synonyme: ASIP antikoerper, Baz antikoerper, PAR3 antikoerper, PAR3alpha antikoerper, PARD-3 antikoerper, PARD3A antikoerper, SE2-5L16 antikoerper, SE2-5LT1 antikoerper, SE2-5T2 antikoerper, Par3 antikoerper, AA960621 antikoerper, AI256638 antikoerper, D8Ertd580e antikoerper, PAR-3 antikoerper, Pard3a antikoerper, asip antikoerper, bazooka antikoerper, par-3 antikoerper, par3 antikoerper, pard3 antikoerper, par-3 family cell polarity regulator antikoerper, partitioning defective 3 homolog antikoerper, par-3 family cell polarity regulator alpha, b antikoerper, par-3 family cell polarity regulator S homeolog antikoerper, PARD3 antikoerper, Pard3 antikoerper, LOC100551156 antikoerper, LOC100473914 antikoerper, pard3 antikoerper, pard3ab antikoerper, pard3.S antikoerper

Hintergrund:

Synonyms: Baz, ASIP, PAR3, PARD-3, PARD3A, SE2-5T2, PPP1R118, SE2-5L16, SE2-5LT1, PAR3alpha, Partitioning defective 3 homolog, PAR-3, Atypical PKC isotype-specific-interacting protein, CTCL tumor antigen se2-5, PAR3-alpha, PARD3, PAR3A

Background: Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.

Gen-ID: 56288

UniProt: Q8TEW0

Pathways: Cell-Cell Junction Organization