SRPK1 Antikörper (AA 551-655)

Produktnummer ABIN681748

Produktdetails anti-SRPK1 Antikörper

Target: SRPK1 (SRSF Protein Kinase 1 (SRPK1))

Bindungsspezifität: AA 551-655

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRPK1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SRPK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SRPK1

Target: SRPK1 (SRSF Protein Kinase 1 (SRPK1))

Andere Bezeichnung: SRPK1 (SRPK1 Produkte)

Synonyme: SFRSK1 antikoerper, AU017960 antikoerper, BEST:CK01209 antikoerper, CG11489 antikoerper, CG9085 antikoerper, CK01209 antikoerper, Dmel\\CG11489 antikoerper, SRPK antikoerper, SRPK1 antikoerper, Srpk79D antikoerper, atc antikoerper, srpk1 antikoerper, zgc:63789 antikoerper, wu:fc06h03 antikoerper, zgc:158800 antikoerper, sfrsk1 antikoerper, SRSF protein kinase 1 antikoerper, serine/arginine-rich protein specific kinase 1 antikoerper, Serine-arginine protein kinase at 79D antikoerper, SRSF protein kinase 1a antikoerper, SRSF protein kinase 1b antikoerper, SRSF protein kinase 1 S homeolog antikoerper, SRPK1 antikoerper, Srpk1 antikoerper, Srpk79D antikoerper, srpk1a antikoerper, srpk1b antikoerper, srpk1.S antikoerper

Hintergrund:

Synonyms: Serine/arginine rich protein specic kinase 1, Serine/arginine-rich protein-specic kinase 1, Serine/threonine protein kinase SRPK1, Serine/threonine-protein kinase SRPK1, SFRS protein kinase 1, SR protein kinase 1, SR protein specic kinase 1, SR-protein-specic kinase 1, SRPK1, SRPK1_HUMAN.

Background: Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Hyperphosphorylates RS domain-containing proteins such as SFRS1, SFRS2 and ZRSR2 on serine residues during metaphase but at lower levels during interphase. Locks onto SFRS1 to form a stable complex and processively phosphorylates the RS domain. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.

Gen-ID: 6732

Pathways: Toll-Like Receptors Cascades