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ARFIP2 Antikörper (pSer260)

ARFIP2 Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN682783
  • Target Alle ARFIP2 Antikörper anzeigen
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Bindungsspezifität
    • 15
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer260
    Reaktivität
    • 31
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 29
    • 2
    Kaninchen
    Klonalität
    • 30
    • 1
    Polyklonal
    Konjugat
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARFIP2 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 13
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human arfaptin 2 around the phosphorylation site of Ser260
    Isotyp
    IgG
    Top Product
    Discover our top product ARFIP2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Andere Bezeichnung
    arfaptin 2 (ARFIP2 Produkte)
    Synonyme
    POR1 antikoerper, 2310002N04Rik antikoerper, POR antikoerper, Por1 antikoerper, ARFIP2 antikoerper, im:7136059 antikoerper, zgc:112066 antikoerper, ADP ribosylation factor interacting protein 2 antikoerper, ADP-ribosylation factor interacting protein 2 antikoerper, ADP-ribosylation factor interacting protein 2b antikoerper, ARFIP2 antikoerper, Arfip2 antikoerper, arfip2b antikoerper
    Hintergrund

    Synonyms: ADP ribosylation factor interacting protein 2, Arfaptin 2, ARFIP2, Partner of RAC1, POR1, ARFP2_HUMAN.

    Background: ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.

    Gen-ID
    23647
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