Ephrin B1 Antikörper (pTyr324, pTyr329)

Produktnummer ABIN684553

Produktdetails anti-Ephrin B1 Antikörper

Target: Ephrin B1 (EFNB1)

Bindungsspezifität: pTyr324, pTyr329

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: These phosphorylation sites are homologous to Tyr323 + Tyr328 in Mouse.

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Ephrin B around the phosphorylation site of Tyr324/329

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Ephrin B1

Target: Ephrin B1 (EFNB1)

Andere Bezeichnung: EFNB1 (EFNB1 Produkte)

Synonyme: EFNB1 antikoerper, LERK2 antikoerper, Cek5-L antikoerper, EFL-3 antikoerper, Elk-L antikoerper, Epl2 antikoerper, Eplg2 antikoerper, LERK-2 antikoerper, Lerk2 antikoerper, Stra1 antikoerper, CFND antikoerper, CFNS antikoerper, EFL3 antikoerper, EPLG2 antikoerper, cfnd antikoerper, cfns antikoerper, efl3 antikoerper, efnb1-A antikoerper, ephrinB1 antikoerper, eplg2 antikoerper, lerk2 antikoerper, ephrin B1 antikoerper, ephrin-B1 antikoerper, ephrin-B1 L homeolog antikoerper, EFNB1 antikoerper, Efnb1 antikoerper, efnb1 antikoerper, efnb1.L antikoerper

Hintergrund:

Synonyms: CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2, Ephrin-B1, EFL-3, ELK ligand, EPH-related receptor tyrosine kinase ligand 2, LERK-2, EFNB1

Background: Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).

Gen-ID: 1947

UniProt: P98172

Pathways: RTK Signalweg