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FOXO3 Antikörper (pSer253)

FOXO3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN684718
  • Target Alle FOXO3 Antikörper anzeigen
    FOXO3 (Forkhead Box O3 (FOXO3))
    Bindungsspezifität
    • 33
    • 13
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer253
    Reaktivität
    • 165
    • 114
    • 105
    • 10
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 161
    • 5
    • 1
    • 1
    Kaninchen
    Klonalität
    • 153
    • 15
    Polyklonal
    Konjugat
    • 69
    • 14
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FOXO3 Antikörper ist unkonjugiert
    Applikation
    • 97
    • 59
    • 52
    • 32
    • 22
    • 15
    • 14
    • 13
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This phosphorylation site is homologous to Ser252 in Mouse and Rat.
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Sheep,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human FoxO3a around the phosphorylation site of Ser253
    Isotyp
    IgG
    Top Product
    Discover our top product FOXO3 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Morales, Abrigo, Acuña, Santos, Bader, Brandan, Simon, Olguin, Cabrera, Cabello-Verrugio: "Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas." in: Disease models & mechanisms, Vol. 9, Issue 4, pp. 441-9, (2016) (PubMed).

  • Target
    FOXO3 (Forkhead Box O3 (FOXO3))
    Andere Bezeichnung
    Foxo3a (FOXO3 Produkte)
    Synonyme
    AF6q21 antikoerper, FKHRL1 antikoerper, FKHRL1P2 antikoerper, FOXO2 antikoerper, FOXO3A antikoerper, zgc:92176 antikoerper, wu:fb50g02 antikoerper, wu:fi33f07 antikoerper, Fkhrl1 antikoerper, Foxo3a antikoerper, FoxO3A antikoerper, 1110048B16Rik antikoerper, 2010203A17Rik antikoerper, C76856 antikoerper, Fkhr2 antikoerper, FOXO-3 antikoerper, FOXO3 antikoerper, foxo3a antikoerper, xfoxo3 antikoerper, foxO3 antikoerper, foxO antikoerper, fkhr antikoerper, foxo5 antikoerper, wu:fj65a12 antikoerper, zFkhr antikoerper, forkhead box O3 antikoerper, forkhead box O3A antikoerper, forkhead box O3 L homeolog antikoerper, forkhead box O3b antikoerper, FOXO3 antikoerper, foxo3a antikoerper, Foxo3 antikoerper, foxo3.L antikoerper, foxo3 antikoerper, foxO3 antikoerper, foxo3b antikoerper
    Hintergrund

    Synonyms: FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2, Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1, FOXO3

    Background: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34C expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

    Gen-ID
    2309
    UniProt
    O43524
    Pathways
    Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis
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