ITGAV/ITGB5 Antikörper

Produktnummer ABIN685372

Produktdetails anti-ITGAV/ITGB5 Antikörper

Target: ITGAV/ITGB5 (Integrin alpha V / beta 5 (ITGAV/ITGB5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGAV/ITGB5 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Integrin beta 5 and Integrin alpha V

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-ITGAV/ITGB5 Antikörper (ABIN685372)

Bian, Ma, Jain, Crane, Kebaish, Wan, Zhang, Edward Guo, Sponseller, Séguin, Riley, Wang, Cao: "Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis." in: Bone research, Vol. 5, pp. 17008, (2017) (PubMed).

Chen, Zheng, Liu, Shi, Qi: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." in: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).

Mondal, Barui, Chaudhuri: "The relationship between the cyclic-RGDfK ligand and ?v?3 integrin receptor." in: Biomaterials, Vol. 34, Issue 26, pp. 6249-60, (2013) (PubMed).

Details zu ITGAV/ITGB5

Target: ITGAV/ITGB5 (Integrin alpha V / beta 5 (ITGAV/ITGB5))

Andere Bezeichnung: Integrin Alpha V + Beta 5 (ITGAV/ITGB5 Produkte)

Hintergrund:

Synonyms: CD51, MSK8, VNRA, VTNR, Integrin alpha-V, Vitronectin receptor subunit alpha, ITGAV

Background: The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Gen-ID: 3685

UniProt: P06756