GADD45A Antikörper (AA 65-165)

Produktnummer ABIN685432

Produktdetails anti-GADD45A Antikörper

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Bindungsspezifität: AA 65-165

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GADD45A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GADD45

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-GADD45A Antikörper (ABIN685432)

Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).

Details zu GADD45A

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Andere Bezeichnung: GADD45 (GADD45A Produkte)

Synonyme: MGC53491 antikoerper, zgc:91795 antikoerper, gadd45a antikoerper, GADD45A antikoerper, ddit1 antikoerper, gadd45 antikoerper, GADD45 antikoerper, AA545191 antikoerper, Ddit1 antikoerper, DDIT1 antikoerper, Gadd45 antikoerper, growth arrest and DNA damage inducible alpha L homeolog antikoerper, growth arrest and DNA-damage-inducible, alpha, b antikoerper, growth arrest and DNA damage inducible alpha antikoerper, growth arrest and DNA damage-inducible protein 45 antikoerper, growth arrest and DNA-damage-inducible 45 alpha antikoerper, growth arrest and DNA-damage-inducible, alpha antikoerper, gadd45a.L antikoerper, gadd45ab antikoerper, GADD45A antikoerper, gadd45a antikoerper, GADD45 antikoerper, Gadd45a antikoerper

Hintergrund:

Synonyms: DDIT1, GADD45, Growth arrest and DNA damage-inducible protein GADD45 alpha, DNA damage-inducible transcript 1 protein, DDIT-1, GADD45A

Background: In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes, stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.

Gen-ID: 1647

UniProt: P24522

Pathways: p53 Signalweg, Zellzyklus