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AKAP12 Antikörper (AA 701-900)

AKAP12 Reaktivität: Ratte, Maus WB, ELISA, IHC (p), IHC (fro), FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN685732
  • Target Alle AKAP12 Antikörper anzeigen
    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
    Bindungsspezifität
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 701-900
    Reaktivität
    • 22
    • 4
    • 2
    • 2
    Ratte, Maus
    Wirt
    • 19
    • 3
    • 2
    • 2
    Kaninchen
    Klonalität
    • 25
    • 1
    Polyklonal
    Konjugat
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AKAP12 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human of human AKAP12
    Isotyp
    IgG
    Top Product
    Discover our top product AKAP12 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
    Andere Bezeichnung
    AKAP12/Gravin (AKAP12 Produkte)
    Synonyme
    akap12 antikoerper, cb27 antikoerper, esr1 antikoerper, fb72g12 antikoerper, id:ibd1202 antikoerper, sb:cb27 antikoerper, si:ch73-192g21.1 antikoerper, wu:fb72g12 antikoerper, wu:fc21c03 antikoerper, AKAP12 antikoerper, AI317366 antikoerper, SSeCKS antikoerper, Srcs5 antikoerper, Tsga12 antikoerper, AKAP12A antikoerper, AKAP12B antikoerper, AKAP12G antikoerper, AKAP250 antikoerper, A kinase (PRKA) anchor protein 12b antikoerper, A-kinase anchoring protein 12 antikoerper, A kinase (PRKA) anchor protein (gravin) 12 antikoerper, akap12b antikoerper, AKAP12 antikoerper, Akap12 antikoerper
    Hintergrund

    Synonyms: A kinase PRKA anchor protein gravin 12, A kinase Anchor Protein 12, A kinase anchor protein 250 kDa, AKAP 12, AKAP 250, AKAP250, DKFZp686M0430, DKFZp686O0331, Gercelin, Gravin, Kinase scaffold protein gravin, Myasthenia gravis autoantigen gravin, Srcs5, SSeCKS, Tsga12.

    Background: Gravin (also known as A Kinase Anchor Protein 12, AKAP12) was cloned from a cDNA expression library screened with serum, from a myasthenia gravis patient. to Gravin were found in 22 out of 72 myasthemia gravis patients and absent in sera of normal individuals. This protein is a myristoylated high molecular weight cytoplasmic protein expressed in endothelial cells, cultured fibroblasts and osteosarcoma cells and highly expressed in the brain. Gravin can bind kinases like PKA and PKC by different domains of the protein and can localize these kinases to specific domains in the cell. Upon differentiation of NT2 cells to neurons (NT2 N), Gravin expression is up regulated and enriched at the inner peripheral cortex in close proximity to the plasma membrane. In differentiated cells, gravin is co-localized with PKCbII, PKCa and PKA. Decreased binding of PKCa to gravin was found after activation of PKC.

    Gen-ID
    9590
    Pathways
    cAMP Metabolic Process
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