KLF6 Antikörper

Produktnummer ABIN685927

Produktdetails anti-KLF6 Antikörper

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLF6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:100-1000, IHC-P: 1:100-500, IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu KLF6

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Andere Bezeichnung: Klf6/Pac1 (KLF6 Produkte)

Hintergrund:

Synonyms: Kruppel-like factor 6, B cell derived protein 1, BCD1, COPEB, Core promoter element-binding protein, CPBP, GC rich sites binding factor GBF, Krueppel-like factor 6, Proto-oncogene BCD1, Transcription factor Zf9, Zf9, CBA1, DKFZp686N0199, GBF, PAC1, ST12, KLF6_HUMAN.

Background: KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene.

Gen-ID: 1316