Cathepsin L Antikörper (AA 71-170)

Produktnummer ABIN687532

Produktdetails anti-Cathepsin L Antikörper

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Bindungsspezifität: AA 71-170

Reaktivität: Human, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Schwein, Ratte

Homologie: Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse capsin L1 proprotein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Cathepsin L Antikörper (ABIN687532)

Hernáez, Guerra, Salas, Andrés: "African Swine Fever Virus Undergoes Outer Envelope Disruption, Capsid Disassembly and Inner Envelope Fusion before Core Release from Multivesicular Endosomes." in: PLoS pathogens, Vol. 12, Issue 4, pp. e1005595, (2016) (PubMed).

Details zu Cathepsin L

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Andere Bezeichnung: Cathepsin L (CTSL1 Produkte)

Synonyme: CATL antikoerper, CTSL1 antikoerper, MEP antikoerper, 1190035F06Rik antikoerper, Ctsl1 antikoerper, fs antikoerper, nkt antikoerper, CATHL antikoerper, CatL antikoerper, Ctsl antikoerper, CTSL antikoerper, mep antikoerper, catl antikoerper, ctsl antikoerper, cpl-1 antikoerper, MGC80629 antikoerper, MGC107932 antikoerper, LOC663234 antikoerper, 26-29-p antikoerper, Cp1 antikoerper, si:dkey-121a11.6 antikoerper, CTSV antikoerper, catL antikoerper, cb15 antikoerper, ctsl1b antikoerper, hgg1 antikoerper, wu:fb30g09 antikoerper, zgc:92089 antikoerper, cathepsin L antikoerper, cathepsin V antikoerper, cathepsin L L homeolog antikoerper, cathepsin L1 antikoerper, Cathepsin L1 antikoerper, Cathepsin L antikoerper, testin gene antikoerper, cathepsin 12 antikoerper, cathepsin Lb antikoerper, cathepsin L.1 antikoerper, CTSL antikoerper, Ctsl antikoerper, CTSV antikoerper, ctsl.L antikoerper, ctsl antikoerper, LOC100008830 antikoerper, catl1 antikoerper, 26-29-p antikoerper, catl antikoerper, Tsp_11596 antikoerper, Testin antikoerper, cts12 antikoerper, LOC102156614 antikoerper, ctslb antikoerper, ctsl.1 antikoerper

Hintergrund:

Synonyms: fs, MEP, nkt, Ctsl1, 1190035F06Rik, Cathepsin L1, Cathepsin L, Major excreted protein, p39 cysteine proteinase, Ctsl

Background: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.

Gen-ID: 13039

UniProt: P06797

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades