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Cadherin Antikörper (AA 841-882) (Biotin)

Reaktivität: Human, Maus WB, IHC (p), ELISA, IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN687684
  • Target Alle Cadherin Produkte
    Cadherin
    Bindungsspezifität
    • 15
    • 8
    • 2
    • 2
    • 1
    • 1
    AA 841-882
    Reaktivität
    • 24
    • 22
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    Human, Maus
    Wirt
    • 22
    • 4
    Kaninchen
    Klonalität
    • 21
    • 5
    Polyklonal
    Konjugat
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cadherin Antikörper ist konjugiert mit Biotin
    Applikation
    • 23
    • 15
    • 14
    • 13
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human E-cadherin
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Cadherin
    Abstract
    Cadherin Produkte
    Synonyme
    ci-cadherin antikoerper, cadherin antikoerper, ci-cadherin antikoerper, LOC430062 antikoerper
    Hintergrund

    Synonyms: UVO, CDHE, ECAD, LCAM, Arc-1, CD324, Cadherin-1, CAM 12/8, Epithelial cadherin, E-cadherin, Uvomorulin, CDH1

    Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.

    Gen-ID
    999
    UniProt
    P12830
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