CD46 Antikörper (AA 251-355)
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- Target Alle CD46 Antikörper anzeigen
- CD46
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Bindungsspezifität
- AA 251-355
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD46 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from Mouse CD46
- Isotyp
- IgG
- Top Product
- Discover our top product CD46 Primärantikörper
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anti-CD46 (CD46) (AA 35-179) antibody
CD46 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 1A5A5 unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 Reaktivität: Human WB, FACS, ELISA, ICC Wirt: Maus Monoclonal 5A8C11 unconjugated
anti-CD46 (CD46) (AA 40-320) antibodyCD46 Reaktivität: Human WB, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) (AA 317-343) antibodyCD46 Reaktivität: Human WB, FACS, IF, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) (AA 317-343), (C-Term) antibodyCD46 Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB21743 unconjugated
anti-CD46 (CD46) antibody (Biotin)CD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 Biotin
anti-CD46 (CD46) antibody (FITC)CD46 Reaktivität: Human, Rind (Kuh) FACS Wirt: Maus Monoclonal MEM-258 FITC
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Monoclonal 7D12 unconjugated Recombinant Antibody
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CD46
- Andere Bezeichnung
- CD46/MCP (CD46 Produkte)
- Hintergrund
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Synonyms: MCP, TLX, AHUS2, MIC10, TRA2.10, Membrane cofactor protein, Trophoblast leukocyte common antigen, CD46
Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
- Gen-ID
- 4179
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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