CD46 Antikörper (AA 251-355)
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- Target Alle CD46 Antikörper anzeigen
- CD46
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Bindungsspezifität
- AA 251-355
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD46 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from Mouse CD46
- Isotyp
- IgG
- Top Product
- Discover our top product CD46 Primärantikörper
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anti-CD46 (CD46) (AA 35-179) antibody
CD46 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 1A5A5 unconjugated
anti-CD46 (CD46) (AA 40-320) antibodyCD46 Reaktivität: Human WB, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) (AA 317-343) antibodyCD46 Reaktivität: Human WB, FACS, ELISA, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) (AA 317-343), (C-Term) antibodyCD46 Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB21743 unconjugated
anti-CD46 (CD46) antibody (FITC)CD46 Reaktivität: Human, Rind (Kuh) FACS Wirt: Maus Monoclonal MEM-258 FITC
anti-CD46 (CD46) antibody (Biotin)CD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 Biotin
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Monoclonal 7D12 unconjugated Recombinant Antibody
anti-CD46 (CD46) antibody (APC)CD46 Reaktivität: Human, Rind (Kuh) FACS Wirt: Maus Monoclonal MEM-258 APC
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CD46
- Andere Bezeichnung
- CD46/MCP (CD46 Produkte)
- Synonyme
- AHUS2 antikoerper, MCP antikoerper, MIC10 antikoerper, TLX antikoerper, TRA2.10 antikoerper, Mcp antikoerper, CD46 antikoerper, CD46 molecule antikoerper, CD46 antigen, complement regulatory protein antikoerper, CD46 molecule, complement regulatory protein antikoerper, membrane cofactor protein-like antikoerper, CD46 antikoerper, Cd46 antikoerper, LOC100341359 antikoerper, LOC103789310 antikoerper
- Hintergrund
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Synonyms: MCP, TLX, AHUS2, MIC10, TRA2.10, Membrane cofactor protein, Trophoblast leukocyte common antigen, CD46
Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
- Gen-ID
- 4179
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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