NPAS4 Antikörper (AA 597-802) (Atto 488)

Produktnummer ABIN6932481

Produktdetails anti-NPAS4 Antikörper (Atto 488)

Target: NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))

Bindungsspezifität: AA 597-802

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NPAS4 Antikörper ist konjugiert mit Atto 488

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Highly expressed in the brain, with lower expression found in endocrine tissue.,Detects ~90 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Fusion protein amino acids 597-802 (C-terminus) of rat Npas4.

Klon: S408-79

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF(1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

A 1:100 dilution of ABIN6932481 was sufficient for detection of NPAS4 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu NPAS4

Target: NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))

Andere Bezeichnung: NPAS4 (NPAS4 Produkte)

Synonyme: LE-PAS antikoerper, Nxf antikoerper, Le-PAS antikoerper, NXF antikoerper, PASD10 antikoerper, bHLHe79 antikoerper, npas4 antikoerper, wu:fj52d04 antikoerper, zgc:136764 antikoerper, MGC146621 antikoerper, neuronal PAS domain protein 4 antikoerper, neuronal PAS domain protein 4a antikoerper, neuronal PAS domain-containing protein 4 antikoerper, Npas4 antikoerper, NPAS4 antikoerper, npas4a antikoerper, npas4 antikoerper, Tsp_02837 antikoerper

Hintergrund: NPAS4 belongs to the Per-Arnt-Sim family of neuronal specific transciption factors, all involved in the development and maintenance of learning and memory pathways (1). NPAS4 is a transcription factor that regulates the formation and maintenance of inhibitory synapses, and can activate the CNS midline enhancer element and the expression of the drebrin gene. Deregulation has been to be associated with developmental disorders such as schizophrenia and autism (2).

Gen-ID: 266734

NCBI Accession: NP_705890

UniProt: Q8CJH6