VPS35 Antikörper

Produktnummer ABIN6932980

Produktdetails anti-VPS35 Antikörper

Target: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VPS35 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Ubiquitous. Highly expressed in brain, colon, heart, kidney, ovary, placenta, skeletal muscle, small intestine, testis, thymus.,Detects ~92 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Full length recombinant human VSP35

Klon: 10A8

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:200)
• IP (1:200)
• optimal dilutions for assays should be determined by the user.

Kommentare:

A 1:1000 dilution of ABIN6932980 was sufficient for detection of VPS35 in 10 μg of SH-SY5Y by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu VPS35

Target: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Andere Bezeichnung: VPS35 (VPS35 Produkte)

Synonyme: MEM3 antikoerper, PARK17 antikoerper, vps35 antikoerper, MGC81959 antikoerper, bZ34G2.3 antikoerper, si:rp71-34g2.3 antikoerper, wu:fa66e03 antikoerper, wu:fb95c08 antikoerper, zgc:136268 antikoerper, 23.m05999 antikoerper, Mem3 antikoerper, VPS35 antikoerper, DKFZp459E1510 antikoerper, CG5625 antikoerper, DVps35 antikoerper, Dmel\\CG5625 antikoerper, Dvps35 antikoerper, dvps35 antikoerper, AI647796 antikoerper, mem3 antikoerper, VPS35, retromer complex component antikoerper, VPS35 retromer complex component L homeolog antikoerper, VPS35 retromer complex component antikoerper, vacuolar protein sorting 35 homolog (S. cerevisiae) antikoerper, vacuolar protein sorting-associated protein 35 antikoerper, vacuolar protein sorting 35 antikoerper, Vacuolar protein sorting 35 antikoerper, hypothetical protein antikoerper, VPS35 retromer complex component S homeolog antikoerper, retromer complex subunit Vps35 antikoerper, VPS35 antikoerper, vps35.L antikoerper, vps35 antikoerper, Tc00.1047053511367.170 antikoerper, Tb10.70.5460 antikoerper, BBOV_IV009740 antikoerper, CC1G_12185 antikoerper, PTRG_08682 antikoerper, CMU_017400 antikoerper, PHATR_43830 antikoerper, MCYG_00751 antikoerper, MGYG_01212 antikoerper, EHI_086580 antikoerper, EHI_002990 antikoerper, EHI_041950 antikoerper, EHI_096520 antikoerper, Bm1_44045 antikoerper, LOC100285267 antikoerper, Vps35 antikoerper, PGTG_10018 antikoerper, Tsp_09825 antikoerper, vps35.S antikoerper

Hintergrund: Vacuolar Protein Sorter-35 (VPS35) is a component of the retromer complex, which is essential for endosome-to-Golgi retrieval of membrane proteins. VPS35 mutations such as D620N have been linked to Parkinson's Disease (PD) (1,2) and affect retromer function, protein homeostasis, and mitochondria (3).

Gen-ID: 55737

NCBI Accession: NP_060676

UniProt: Q96QK1