KRT77, KRT76 Antikörper (FITC)

Produktnummer ABIN6933729

Produktdetails

Target: KRT77, KRT76

Reaktivität: Human, Ratte, Huhn, Rind (Kuh), Hund, Affe, Maus, Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: FITC

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Aufreinigung: Purified by Protein A/G

Immunogen: Human epidermal keratin

Klon: AE-1-AE-3

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Skin, Adeno- or Squamous carcinomas.

Known Application: Flow Cytometry: 5 µL per test per one million cells (or 5 µL per 100 µL of whole blood)Immunofluorescence (1:50-1:100)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Antigendetails

Target: KRT77, KRT76

Andere Bezeichnung: KRT77 & KRT76

Hintergrund: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE-1/AE-3 is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

Molekulargewicht: 40-67kDa

Gen-ID: 374454, 51350

UniProt: Q7Z794, Q01546