Glypican 3 Antikörper (AA 511-580) (CF®555)
-
- Target Alle Glypican 3 (GPC3) Antikörper anzeigen
- Glypican 3 (GPC3)
-
Bindungsspezifität
- AA 511-580
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Glypican 3 Antikörper ist konjugiert mit CF®555
-
Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Staining Methods (StM)
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- A recombinant fragment containing amino acids 511-580 of human glypican-3
- Klon
- SPM595
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product GPC3 Primärantikörper
-
-
- Applikationshinweise
-
Positive Control: 293T cells. Hepatocellular carcinoma.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 100 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
-
- Target
- Glypican 3 (GPC3)
- Andere Bezeichnung
- GPC3 (GPC3 Produkte)
- Synonyme
- GPC3 antikoerper, sgb antikoerper, dgsx antikoerper, sdys antikoerper, sgbs antikoerper, oci-5 antikoerper, sgbs1 antikoerper, DGSX antikoerper, GTR2-2 antikoerper, MXR7 antikoerper, OCI-5 antikoerper, SDYS antikoerper, SGB antikoerper, SGBS antikoerper, SGBS1 antikoerper, Glypican-3 antikoerper, glypican 3 antikoerper, gpc3 antikoerper, GPC3 antikoerper, Gpc3 antikoerper
- Hintergrund
- Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100 % in follicular carcinoma and 70 % in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.
- Molekulargewicht
- 67kDa
- Gen-ID
- 2719
- UniProt
- P51654
- Pathways
- Glycosaminoglycan Metabolic Process
-