ATRX Antikörper
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- Target Alle ATRX Antikörper anzeigen
- ATRX (helicase 2, X-linked (ATRX))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ATRX Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 thalassemia or ATRX syndrome
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human ATRX protein
- Klon
- 39f
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product ATRX Primärantikörper
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- Applikationshinweise
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Raji, HeLa or A431 cells. Pancreas, Adrenal, Ovary, Kidney, Prostate or Stomach.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- ATRX (helicase 2, X-linked (ATRX))
- Andere Bezeichnung
- ATRX (ATRX Produkte)
- Synonyme
- ATR2 antikoerper, JMS antikoerper, MRXHF1 antikoerper, RAD54 antikoerper, RAD54L antikoerper, SFM1 antikoerper, SHS antikoerper, XH2 antikoerper, XNP antikoerper, ZNF-HX antikoerper, 4833408C14Rik antikoerper, AI447451 antikoerper, DXHXS6677E antikoerper, HP1-BP38 antikoerper, Hp1bp2 antikoerper, Hp1bp38 antikoerper, MRXS3 antikoerper, Rad54 antikoerper, Xnp antikoerper, atrx antikoerper, rad54 antikoerper, atrxl antikoerper, wu:fb26e12 antikoerper, wu:fb52h08 antikoerper, wu:fb72g09 antikoerper, wu:fb94e07 antikoerper, zgc:66223 antikoerper, ATRX, chromatin remodeler antikoerper, alpha thalassemia/mental retardation syndrome X-linked L homeolog antikoerper, alpha thalassemia/mental retardation syndrome X-linked homolog (human) antikoerper, ATRX antikoerper, Atrx antikoerper, atrx.L antikoerper, atrx antikoerper
- Hintergrund
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Alpha thalassemia/mental retardation syndrome X linked homolog, ATP-dependent helicase ATRX, ATR2, ATRX, DNA-dependent ATPase and helicase, MRXHF1, RAD54, RAD54L, SFM1, SHS, Transcriptional regulator ATRX, X-linked helicase II, X-linked nuclear protein, XH2, XNP, Znf-HX,ATRX / RAD54 (Alpha Thalassemia Mental Retardation)
Cellular localisation: Nuclear - Molekulargewicht
- 280kDa
- Gen-ID
- 546, 533526, 653797
- UniProt
- P46100
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