CD207 Antikörper (AA 74-213)
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- Target Alle CD207 Antikörper anzeigen
- CD207 (CD207 Molecule, Langerin (CD207))
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Bindungsspezifität
- AA 74-213
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD207 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Coating (Coat)
- Spezifität
- Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
- Klon
- LGRN-1821
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product CD207 Primärantikörper
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- Applikationshinweise
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or A549 cells (WB).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- CD207 (CD207 Molecule, Langerin (CD207))
- Andere Bezeichnung
- CD207 (CD207 Produkte)
- Synonyme
- CD207 antikoerper, CLEC4K antikoerper, RGD1565913 antikoerper, CD207 molecule antikoerper, CD207 antigen antikoerper, CD207 antikoerper, Cd207 antikoerper
- Hintergrund
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C-type lectin domain family 4 member K, CD207, CLEC4K, Langerhans cell specific c type lectin, Langerin,Langerin / CD207 (Marker of Langerhans Cells)
Cellular localisation: Cell surface and cytoplasmic - Molekulargewicht
- 48kDa
- Gen-ID
- 50489, 199731
- UniProt
- Q9UJ71
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