Hepatocyte Specific Antigen Antikörper

Produktnummer ABIN6937371

Produktdetails anti-Hepatocyte Specific Antigen Antikörper

Target: Hepatocyte Specific Antigen (HepPar-1)

Reaktivität: Human, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Hepatocyte Specific Antigen Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC), Staining Methods (StM)

Aufreinigung: Purified by Protein A/G

Immunogen: Extract of a formalin-fixed, rejected-allograft of a human liver

Klon: OCH1E5

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Liver or Hepatocellular Carcinoma (HCC).

Known Application: Immunofluorescence (0.5-1.0 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 10 mM PBS without BSA and without Azide.

Konservierungsmittel: Azide free

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

Haltbarkeit: 24 months

Details zu Hepatocyte Specific Antigen

Target: Hepatocyte Specific Antigen (HepPar-1)

Andere Bezeichnung: Hepatocyte Specific Antigen (Hepatocellular Marker) (HepPar-1 Produkte)

Hintergrund: Hepatocyte Specific Antigen, also called Hepatocyte Paraffin 1 or HepPar1, localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC's occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.