HLA-ABC Antikörper
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- Target Alle HLA-ABC Antikörper anzeigen
- HLA-ABC
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser HLA-ABC Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Spezifität
- Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
- Kreuzreaktivität (Details)
- Human. Mouse. Non-Human primates.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Human peripheral blood leukocytes
- Klon
- 246-B8-E7
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product HLA-ABC Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: THP-1 and Jurkat cells. Tonsil or lymph node.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- HLA-ABC
- Andere Bezeichnung
- HLA-A, HLA-B, HLA-C (HLA-ABC Produkte)
- Synonyme
- HLAA antikoerper, major histocompatibility complex, class I, A antikoerper, HLA-A antikoerper
- Hintergrund
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HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A + B + C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC,HLA-ABC (MHC I)
Cellular localisation: Cell surface - Molekulargewicht
- ~41kDa
- Gen-ID
- 3105, 3106, 3107
- UniProt
- P01889, P30443, P30499
- Pathways
- T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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