IFNA1 Antikörper
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- Target Alle IFNA1 Antikörper anzeigen
- IFNA1 (Interferon, alpha 1 (IFNA1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser IFNA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Purified recombinant human IFN-alpha1
- Klon
- Feb-48
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product IFNA1 Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Immunohistochemistry (frozen), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Stimulated human peripheral blood mononuclear cells.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- IFNA1 (Interferon, alpha 1 (IFNA1))
- Andere Bezeichnung
- IFNA1 (IFNA1 Produkte)
- Synonyme
- IFL antikoerper, IFN antikoerper, IFN-ALPHA antikoerper, IFN-alphaD antikoerper, IFNA13 antikoerper, IFNA@ antikoerper, Ifa1 antikoerper, IFN-ALPHA-1 antikoerper, IFN1@ antikoerper, IFNA1 antikoerper, IFN-alpha antikoerper, IFN-gamma antikoerper, IFNA antikoerper, IFNA2 antikoerper, IFNA6 antikoerper, IFN-alpha1 antikoerper, interferon alpha 13 antikoerper, interferon alpha 1 antikoerper, interferon, alpha 1 antikoerper, interferon, alpha 13 antikoerper, interferon antikoerper, interferon-alpha 1 antikoerper, interferon, alpha, leukocyte antikoerper, interferon-alpha-14 antikoerper, IFNA13 antikoerper, IFNA1 antikoerper, Ifna1 antikoerper, ifna1 antikoerper, IFNA3 antikoerper, IFN-ALPHA-14 antikoerper
- Hintergrund
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IFN alpha, IFN alpha 1/13, IFN alpha 1b, Interferon alpha 13 (IFNA13), Interferon alpha leukocyte (IFL), Interferon alpha-1/13 (IFN-alpha-1/13), Interferon alpha-D (IFN alphaD), Interferon alpha1 (IFNA1), LeIF D,Interferon alpha-1 (IFNA1)
Cellular localisation: Cytoplasmic & Extracellular (Secreted) - Molekulargewicht
- 16-27kDa
- Gen-ID
- 3439, 37026, 533471
- UniProt
- P01562
- Pathways
- JAK-STAT Signalweg, Hepatitis C
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