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Rekombinanter IgL Antikörper

Reaktivität: Human IHC, IHC (f) Wirt: Kaninchen Monoclonal rLLC-1738 unconjugated Recombinant Antibody
Produktnummer ABIN6937551
  • Target Alle IgL Produkte
    IgL
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    Human
    Wirt
    • 10
    • 2
    Kaninchen
    Klonalität
    • 11
    • 1
    Monoklonal
    Konjugat
    • 11
    • 1
    Dieser IgL Antikörper ist unkonjugiert
    Applikation
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Purified human lambda light chain
    Klon
    RLLC-1738
    Isotyp
    IgG1 kappa
  • Applikationshinweise

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human tonsil or spleen tissue (IHC).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    IgL
    Abstract
    IgL Produkte
    Synonyme
    IGL@ antikoerper, IGLC6 antikoerper, igl antikoerper, immunoglobulin lambda locus antikoerper, IGL antikoerper, igl@ antikoerper
    Hintergrund
    Bence Jones Protein, BJP, IGLC 1/2/3, Mcg Marker, Paraprotein,Lambda Light Chain (B-Cell Marker)
    Cellular localisation: Cell Surface, cytoplasmic and secreted
    Molekulargewicht
    ~22.5kDa
    Gen-ID
    3535, 3546, 449585
    UniProt
    P01701, P01842
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