Rekombinanter Prostate Specific Antigen Antikörper

Produktnummer ABIN6937636

Produktdetails anti-Prostate Specific Antigen Antikörper

Target: Prostate Specific Antigen (PSA)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Prostate Specific Antigen Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunostaining (ISt)

Spezifität: Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human KLK3 protein

Klon: KLK3-2871R

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Positive_Control: PC12 cells. Normal prostate or prostate carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Andere Bezeichnung: KLK3 (PSA Produkte)

Synonyme: APS antikoerper, KLK2A1 antikoerper, PSA antikoerper, hK3 antikoerper, KLK3 antikoerper, Klk1c10l2 antikoerper, RSGK-50 antikoerper, RSKG-50 antikoerper, rGK-3 antikoerper, Kal-3 antikoerper, Kal3 antikoerper, Klk3 antikoerper, AAP-S antikoerper, MP100 antikoerper, Psa antikoerper, R74825 antikoerper, goku antikoerper, kallikrein related peptidase 3 antikoerper, kallikrein 3 antikoerper, kallikrein 1-related peptidase C3 antikoerper, kallikrein B, plasma 1 antikoerper, aminopeptidase puromycin sensitive antikoerper, KLK3 antikoerper, Klk1c3 antikoerper, Klkb1 antikoerper, Npepps antikoerper

Hintergrund: Antigen, prostate-specific (APS), Gamma-seminoprotein, hK3, Kallikrein related peptidase 3, Kallikrein-3 (KLK3), KLK2A1, P-30 antigen, Semenogelase, Seminin,Prostate Specific Antigen (PSA)
Cellular localisation: Cytoplasmic

Molekulargewicht: 33-34kDa

Gen-ID: 354, 171995

UniProt: P07288

Pathways: Komplementsystem