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Keratin 5/8 Antikörper

KRT5/8 Reaktivität: Human WB, FACS, IF, IHC (f) Wirt: Maus Monoclonal C-50 unconjugated
Produktnummer ABIN6937713
  • Target Alle Keratin 5/8 (KRT5/8) Produkte
    Keratin 5/8 (KRT5/8)
    Reaktivität
    • 22
    • 16
    • 15
    • 13
    • 13
    • 13
    • 12
    • 10
    • 9
    • 3
    • 2
    • 2
    Human
    Wirt
    • 22
    Maus
    Klonalität
    • 22
    Monoklonal
    Konjugat
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Keratin 5/8 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 15
    • 13
    • 12
    • 8
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    It reacts with keratin 5 (58 kDa) and keratin 8 (52.5 kDa). Simple epithelia express cytokeratin 8 in combination with 18. On the other hand, basal cells of stratified epithelia express cytokeratin 5 paired with 14. This antibody therefore, reacts with a wide range of epithelia and their carcinomas.
    Keine Kreuzreaktivität
    Huhn, Xenopus laevis
    Kreuzreaktivität (Details)
    Human. Pig. Mouse. Rat. Hamster. Cow. Dog. Sheep. Ferret. Does not react with Chicken or Xenopus.
    Immunogen
    Cytoskeletal preparation from HeLa cells
    Klon
    C-50
    Isotyp
    IgG1 kappa
  • Applikationshinweise

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(For staining of formalin-fixed tissues, digest sections with trypsin at 1 mg/mL PBS, 15 min at RT)Optimal dilution for a specific application should be determined.

    Positive_Control: HepG2 or A431 cells. Skin or Squamous cell carcinoma.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2 to 8°C. Antibody is stable for 24 months.
    Haltbarkeit
    24 months
  • Target
    Keratin 5/8 (KRT5/8)
    Andere Bezeichnung
    KRT5 & KRT8 (KRT5/8 Produkte)
    Hintergrund
    CK5, DDD, EBS2, Epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne Types, K5, Keratin complex 2, basic, Gene 5, Keratin Type II Cytoskeletal 5, Keratin-5, KRT5, KRT5A, Type II Cytoskeletal 5, Type-II Keratin Kb5. CK8, CARD2, CYK8, CYKER, Cytokeratin Endo A, DreK8, EndoA, K2C8, K8, Keratin 8, Krt 2.8, KRT8, Type-II Keratin Kb8,Cytokeratin 5/8
    Cellular localisation: Cytoplasmic
    Molekulargewicht
    58kDa (CK5), 52.5kDa (CK8)
    Gen-ID
    3852, 3856, 433845
    UniProt
    P13647, P05787
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