Plakophilin 1 Antikörper (N-Term)

Produktnummer ABIN6938188

Produktdetails anti-Plakophilin 1 Antikörper

Target: Plakophilin 1 (PKP1)

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Plakophilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Spezifität: Recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.

Kreuzreaktivität (Details): Human. Mouse.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: N-terminus of human Plakophilin-1 protein

Klon: 10B2

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: U87, HeLa and A431 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu Plakophilin 1

Target: Plakophilin 1 (PKP1)

Andere Bezeichnung: PKP1 (PKP1 Produkte)

Synonyme: PKP1 antikoerper, fb30d08 antikoerper, wu:fb30d08 antikoerper, AI528551 antikoerper, B6P antikoerper, plakophilin 1 antikoerper, plakophilin 1b antikoerper, PKP1 antikoerper, pkp1b antikoerper, Pkp1 antikoerper

Hintergrund: B6P, Band 6 protein, PKP1, Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome),Plakophilin-1 (PKP1)
Cellular localisation: Cell Surface and nuclear

Molekulargewicht: 75kDa

Gen-ID: 5317, 497350

UniProt: Q13835