SHBG Antikörper
-
- Target Alle SHBG Antikörper anzeigen
- SHBG (Sex Hormone Binding Globulin (SHBG))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser SHBG Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human SHBG protein
- Klon
- SPM605
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product SHBG Primärantikörper
-
-
- Applikationshinweise
-
Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: Liver, Placenta or Testis.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
-
- Target
- SHBG (Sex Hormone Binding Globulin (SHBG))
- Andere Bezeichnung
- SHBG (SHBG Produkte)
- Synonyme
- ABP antikoerper, SBP antikoerper, TEBG antikoerper, Abpa antikoerper, shbgl antikoerper, wu:fb66h07 antikoerper, wu:fd55b08 antikoerper, zgc:123063 antikoerper, shbg antikoerper, sex hormone binding globulin antikoerper, sex hormone-binding globulin antikoerper, sex hormone binding globulin L homeolog antikoerper, SHBG antikoerper, Shbg antikoerper, shbg antikoerper, shbg.L antikoerper
- Hintergrund
-
Androgen binding protein (ABP), Sex hormone-binding globulin (SHBG), Sex steroid binding protein (SBP), Sex steroid-binding protein, Testis-specific androgen-binding protein, Testosterone binding beta globulin, Testosterone-Estradiol-Binding Globulin (TEBG),Sex Hormone Binding Globulin (SHBG)
Cellular localisation: Cytoplasmic & Extracellular (Secreted) - Molekulargewicht
- 45kDa
- Gen-ID
- 6462, 632235
- UniProt
- P04278
- Pathways
- Hormone Transport
-